SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.

Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA
Cell Metab. 2012 15 (5): 675-90

PMID: 22560220 · PMCID: PMC3545644 · DOI:10.1016/j.cmet.2012.04.003

MeSH Terms (16)

AMP-Activated Protein Kinase Kinases Animals Cells, Cultured Enzyme Activation Hepatocytes Mice Mice, Inbred C57BL Mice, Knockout Mitochondria Muscle, Skeletal NAD Protein Kinases Resveratrol Signal Transduction Sirtuin 1 Stilbenes

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