Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials.

Lovly CM, Dahlman KB, Fohn LE, Su Z, Dias-Santagata D, Hicks DJ, Hucks D, Berry E, Terry C, Duke M, Su Y, Sobolik-Delmaire T, Richmond A, Kelley MC, Vnencak-Jones CL, Iafrate AJ, Sosman J, Pao W
PLoS One. 2012 7 (4): e35309

PMID: 22536370 · PMCID: PMC3335021 · DOI:10.1371/journal.pone.0035309

MeSH Terms (17)

Cell Line, Tumor Clinical Trials as Topic DNA Mutational Analysis Eligibility Determination Genetic Testing GTP-Binding Protein alpha Subunits GTP-Binding Protein alpha Subunits, Gq-G11 Humans Male Melanoma Molecular Diagnostic Techniques Nerve Tissue Proteins Point Mutation Proto-Oncogene Proteins B-raf Proto-Oncogene Proteins c-kit Proto-Oncogene Proteins p21(ras) Skin Neoplasms

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