UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice.

Ainoya K, Moriguchi T, Ohmori S, Souma T, Takai J, Morita M, Chandler KJ, Mortlock DP, Shimizu R, Engel JD, Lim KC, Yamamoto M
Mol Cell Biol. 2012 32 (12): 2312-22

PMID: 22493062 · PMCID: PMC3372261 · DOI:10.1128/MCB.06699-11

MeSH Terms (11)

Animals Bone Morphogenetic Protein 4 Enhancer Elements, Genetic GATA2 Transcription Factor Gene Expression Regulation, Developmental Mesoderm Mice Mutation Urogenital Abnormalities Urogenital System Vesico-Ureteral Reflux

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