Ligand structural motifs can decouple glucocorticoid receptor transcriptional activation from target promoter occupancy.

Blind RD, Pineda-Torra I, Xu Y, Xu HE, Garabedian MJ
Biochem Biophys Res Commun. 2012 420 (4): 839-44

PMID: 22465009 · PMCID: PMC3340612 · DOI:10.1016/j.bbrc.2012.03.084

MeSH Terms (21)

3T3-L1 Cells 17-alpha-Hydroxyprogesterone Adipocytes Adipogenesis Adrenal Cortex Hormones Aldosterone Animals Cell Line, Tumor Corticosterone Desoxycorticosterone Dexamethasone Hydrocortisone Ligands Mice Molecular Structure Progesterone Promoter Regions, Genetic Protein Conformation Rats Receptors, Glucocorticoid Transcriptional Activation

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