Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis.

Tucker EI, Verbout NG, Leung PY, Hurst S, McCarty OJ, Gailani D, Gruber A
Blood. 2012 119 (20): 4762-8

PMID: 22442348 · PMCID: PMC3367876 · DOI:10.1182/blood-2011-10-386185

MeSH Terms (15)

Animals Antibodies, Monoclonal Anticoagulants Blood Coagulation Disorders Coinfection Down-Regulation Factor XIa Immunotherapy Inflammation Male Mice Mice, Inbred C57BL Protein C Sepsis Survival Analysis

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