Systemic elevation of PTEN induces a tumor-suppressive metabolic state.

Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, Anastasiou D, Ito K, Sasaki AT, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, Pandolfi PP
Cell. 2012 149 (1): 49-62

PMID: 22401813 · PMCID: PMC3319228 · DOI:10.1016/j.cell.2012.02.030

MeSH Terms (13)

Animals Body Size Cell Count Cell Proliferation Cell Respiration Energy Metabolism Mice Mice, Transgenic Mitochondria Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-myc PTEN Phosphohydrolase Signal Transduction

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