Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice.

Morgan JA, Cheepala SB, Wang Y, Neale G, Adachi M, Nachagari D, Leggas M, Zhao W, Boyd K, Venkataramanan R, Schuetz JD
J Biol Chem. 2012 287 (18): 14456-66

PMID: 22375007 · PMCID: PMC3340271 · DOI:10.1074/jbc.M111.319681

MeSH Terms (18)

Animals Aryl Hydrocarbon Hydroxylases Cyclic AMP Cyclic AMP Response Element-Binding Protein Cytochrome P450 Family 2 Gene Expression Regulation, Enzymologic Humans Leydig Cells Liver Male Mice Mice, Knockout Multidrug Resistance-Associated Proteins Receptors, LH Spermatogenesis Steroid Hydroxylases Testosterone Up-Regulation

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