Interaction of three regiospecific amino acid residues is required for OATP1B1 gain of OATP1B3 substrate specificity.

DeGorter MK, Ho RH, Leake BF, Tirona RG, Kim RB
Mol Pharm. 2012 9 (4): 986-95

PMID: 22352740 · PMCID: PMC3319192 · DOI:10.1021/mp200629s

MeSH Terms (9)

Amino Acids Cholecystokinin Liver-Specific Organic Anion Transporter 1 Mutagenesis, Site-Directed Organic Anion Transporters Organic Anion Transporters, Sodium-Independent Peptide Fragments Solute Carrier Organic Anion Transporter Family Member 1B3 Substrate Specificity

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