RAF265 inhibits the growth of advanced human melanoma tumors.

Su Y, Vilgelm AE, Kelley MC, Hawkins OE, Liu Y, Boyd KL, Kantrow S, Splittgerber RC, Short SP, Sobolik T, Zaja-Milatovic S, Dahlman KB, Amiri KI, Jiang A, Lu P, Shyr Y, Stuart DD, Levy S, Sosman JA, Richmond A
Clin Cancer Res. 2012 18 (8): 2184-98

PMID: 22351689 · PMCID: PMC3724517 · DOI:10.1158/1078-0432.CCR-11-1122

MeSH Terms (30)

Animals Apoptosis Base Sequence bcl-X Protein Cell Cycle Proteins Cell Proliferation Cyclin D1 Extracellular Signal-Regulated MAP Kinases Female Gene Expression Profiling Humans Imidazoles Ki-67 Antigen Male MAP Kinase Signaling System Melanoma Mice Mice, Nude Mutation Oligonucleotide Array Sequence Analysis Protein-Serine-Threonine Kinases Protein Kinase Inhibitors Proto-Oncogene Proteins Proto-Oncogene Proteins B-raf Proto-Oncogene Proteins c-kit Proto-Oncogene Proteins p21(ras) Pyridines Sequence Analysis, DNA Tumor Cells, Cultured Xenograft Model Antitumor Assays

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