Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors.

Pereira L, Soares P, Máximo V, Samuels DC
BMC Cancer. 2012 12: 53

PMID: 22299657 · PMCID: PMC3342922 · DOI:10.1186/1471-2407-12-53

MeSH Terms (9)

DNA, Mitochondrial Electron Transport Complex I Humans Mitochondrial Proteins Mutation Neoplasms Phenotype Phylogeny Selection, Genetic

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