Arginase II inhibition prevents nitrate tolerance.

Khong SM, Andrews KL, Huynh NN, Venardos K, Aprico A, Michell DL, Zarei M, Moe KT, Dusting GJ, Kaye DM, Chin-Dusting JP
Br J Pharmacol. 2012 166 (7): 2015-23

PMID: 22288373 · PMCID: PMC3402767 · DOI:10.1111/j.1476-5381.2012.01876.x

MeSH Terms (16)

Animals Aorta, Thoracic Arginase Arginine Boronic Acids Drug Tolerance Humans Human Umbilical Vein Endothelial Cells In Vitro Techniques Mice Mice, Inbred C57BL Mice, Knockout Nitric Oxide Synthase Type III Nitroglycerin Reactive Oxygen Species Vasodilator Agents

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