Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios.

Weitkamp JH, Koyama T, Rock MT, Correa H, Goettel JA, Matta P, Oswald-Richter K, Rosen MJ, Engelhardt BG, Moore DJ, Polk DB
Gut. 2013 62 (1): 73-82

PMID: 22267598 · PMCID: PMC3606820 · DOI:10.1136/gutjnl-2011-301551

MeSH Terms (18)

Biomarkers Case-Control Studies CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes Enterocolitis, Necrotizing Female Flow Cytometry Forkhead Transcription Factors Gene Expression Profiling Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases Intestinal Mucosa Lymphocyte Count Male Prospective Studies T-Lymphocytes, Regulatory

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