The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates transforming growth factor (TGF)-β-dependent signaling, and inhibits TGF-β-dependent fibrotic response in skeletal muscles.

Cabello-Verrugio C, Santander C, Cofré C, Acuña MJ, Melo F, Brandan E
J Biol Chem. 2012 287 (9): 6773-87

PMID: 22203668 · PMCID: PMC3307262 · DOI:10.1074/jbc.M111.312488

MeSH Terms (19)

Animals Cell Line CHO Cells Cricetinae Decorin Endocytosis Fibrosis Glyburide Humans Leucine Low Density Lipoprotein Receptor-Related Protein-1 Male Mice Mice, Inbred C57BL Muscle, Skeletal Myoblasts, Skeletal Protein Structure, Tertiary Signal Transduction Transforming Growth Factor beta

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