High proportion of fluoroquinolone-resistant Mycobacterium tuberculosis isolates with novel gyrase polymorphisms and a gyrA region associated with fluoroquinolone susceptibility.

Devasia R, Blackman A, Eden S, Li H, Maruri F, Shintani A, Alexander C, Kaiga A, Stratton CW, Warkentin J, Tang YW, Sterling TR
J Clin Microbiol. 2012 50 (4): 1390-6

PMID: 22189117 · PMCID: PMC3318526 · DOI:10.1128/JCM.05286-11

MeSH Terms (18)

Adult Aged Aged, 80 and over Antitubercular Agents Bacterial Proteins Codon DNA Gyrase DNA Mutational Analysis Drug Resistance, Bacterial Female Fluoroquinolones Humans Male Middle Aged Mutation, Missense Mycobacterium tuberculosis Polymorphism, Genetic Tuberculosis, Pulmonary

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