Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein.

Tep C, Kim ML, Opincariu LI, Limpert AS, Chan JR, Appel B, Carter BD, Yoon SO
J Biol Chem. 2012 287 (2): 1600-8

PMID: 22128191 · PMCID: PMC3256919 · DOI:10.1074/jbc.M111.312736

MeSH Terms (21)

Adaptor Proteins, Signal Transducing Animals Axons Brain-Derived Neurotrophic Factor Carrier Proteins Cell Adhesion Molecules Cell Cycle Proteins Cell Movement Cells, Cultured Mice Myelin Sheath Nerve Tissue Proteins Neuroglia Neuropeptides rac1 GTP-Binding Protein rac GTP-Binding Proteins Rats Schwann Cells Signal Transduction Zebrafish Zebrafish Proteins

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