Clinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation.

Gong IY, Schwarz UI, Crown N, Dresser GK, Lazo-Langner A, Zou G, Roden DM, Stein CM, Rodger M, Wells PS, Kim RB, Tirona RG
PLoS One. 2011 6 (11): e27808

PMID: 22114699 · PMCID: PMC3218053 · DOI:10.1371/journal.pone.0027808

MeSH Terms (25)

Adult Aged Aged, 80 and over Algorithms Anticoagulants Aryl Hydrocarbon Hydroxylases Blood Coagulation Cytochrome P-450 CYP2C9 Cytochrome P-450 Enzyme System Cytochrome P450 Family 4 Dose-Response Relationship, Drug Female Gene Frequency Genotype Humans Kidney Function Tests Male Middle Aged Mixed Function Oxygenases Prospective Studies Tissue Distribution Vitamin K Vitamin K Epoxide Reductases Warfarin Young Adult

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