The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients.

Birdwell KA, Grady B, Choi L, Xu H, Bian A, Denny JC, Jiang M, Vranic G, Basford M, Cowan JD, Richardson DM, Robinson MP, Ikizler TA, Ritchie MD, Stein CM, Haas DW
Pharmacogenet Genomics. 2012 22 (1): 32-42

PMID: 22108237 · PMCID: PMC3237759 · DOI:10.1097/FPC.0b013e32834e1641

MeSH Terms (24)

Adult Age Factors ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1 Body Weight Cytochrome P-450 CYP3A Databases, Nucleic Acid Dose-Response Relationship, Drug Drug Monitoring Electronic Health Records Female Genetic Association Studies Genotype Hemoglobins Humans Immunosuppressive Agents Kidney Transplantation Linkage Disequilibrium Male Middle Aged Polymorphism, Single Nucleotide Pregnane X Receptor Receptors, Steroid Tacrolimus

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