Anti-transforming growth factor ß antibody treatment rescues bone loss and prevents breast cancer metastasis to bone.

Biswas S, Nyman JS, Alvarez J, Chakrabarti A, Ayres A, Sterling J, Edwards J, Rana T, Johnson R, Perrien DS, Lonning S, Shyr Y, Matrisian LM, Mundy GR
PLoS One. 2011 6 (11): e27090

PMID: 22096521 · PMCID: PMC3214031 · DOI:10.1371/journal.pone.0027090

MeSH Terms (17)

Animals Antibodies Bone and Bones Bone Neoplasms Breast Neoplasms Cell Differentiation Cell Line, Tumor Collagen Female Humans Mice Mice, Nude Osteoblasts Osteoclasts Osteogenesis Real-Time Polymerase Chain Reaction Transforming Growth Factor beta

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