Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.

Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, Magnuson MA, Bhushan A, Sussel L
Genes Dev. 2011 25 (21): 2291-305

PMID: 22056672 · PMCID: PMC3219233 · DOI:10.1101/gad.173039.111

MeSH Terms (21)

Animals Cell Differentiation Co-Repressor Proteins Diabetes Mellitus DNA (Cytosine-5-)-Methyltransferases Gene Expression Regulation Ghrelin Glucagon Glucagon-Secreting Cells Homeodomain Proteins Insulin Insulin-Secreting Cells Mice Mutation Organ Specificity Promoter Regions, Genetic Protein Binding Proteins Protein Structure, Tertiary Transcription Factors Zebrafish Proteins

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