(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2.

Duggan KC, Hermanson DJ, Musee J, Prusakiewicz JJ, Scheib JL, Carter BD, Banerjee S, Oates JA, Marnett LJ
Nat Chem Biol. 2011 7 (11): 803-9

PMID: 22053353 · PMCID: PMC3298755 · DOI:10.1038/nchembio.663

MeSH Terms (14)

Arachidonic Acid Arachidonic Acids Cannabinoid Receptor Modulators Catalytic Domain Chemistry, Pharmaceutical Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Endocannabinoids Glycerides Models, Molecular Oxidation-Reduction Protein Binding Protein Conformation Substrate Specificity

Connections (3)

This publication is referenced by other Labnodes entities:

Links