ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer.

Miller TW, Balko JM, Fox EM, Ghazoui Z, Dunbier A, Anderson H, Dowsett M, Jiang A, Smith RA, Maira SM, Manning HC, González-Angulo AM, Mills GB, Higham C, Chanthaphaychith S, Kuba MG, Miller WR, Shyr Y, Arteaga CL
Cancer Discov. 2011 1 (4): 338-51

PMID: 22049316 · PMCID: PMC3204388 · DOI:10.1158/2159-8290.CD-11-0101

MeSH Terms (17)

Animals Breast Neoplasms Cell Line, Tumor Cyclin-Dependent Kinase 4 Down-Regulation Drug Resistance, Neoplasm E2F Transcription Factors Estrogen Receptor alpha Estrogen Receptor Modulators Estrogens Female Gene Expression Humans Mice Mice, Nude Phosphatidylinositol 3-Kinases Transcription, Genetic

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