A fluorescence displacement assay for antidepressant drug discovery based on ligand-conjugated quantum dots.

Chang JC, Tomlinson ID, Warnement MR, Iwamoto H, DeFelice LJ, Blakely RD, Rosenthal SJ
J Am Chem Soc. 2011 133 (44): 17528-31

PMID: 21970724 · PMCID: PMC3235909 · DOI:10.1021/ja204301g

MeSH Terms (17)

Amines Animals Antidepressive Agents Binding Sites Dose-Response Relationship, Drug Drug Discovery Fluorescence Humans Ligands Oocytes Paroxetine Quantum Dots Serotonin Plasma Membrane Transport Proteins Spectrometry, Fluorescence Structure-Activity Relationship Time Factors Xenopus

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