Thrombin induces osteosarcoma growth, a function inhibited by low molecular weight heparin in vitro and in vivo: procoagulant nature of osteosarcoma.

Ichikawa J, Cole HA, Magnussen RA, Mignemi NA, Butler M, Holt GE, O'Rear L, Yuasa M, Pabla B, Haro H, Cates JM, Hamm HE, Schwartz HS, Schoenecker JG
Cancer. 2012 118 (9): 2494-506

PMID: 21953059 · DOI:10.1002/cncr.26518

MeSH Terms (17)

Adolescent Adult Animals Blood Coagulation Bone Neoplasms Cell Line, Tumor Cell Proliferation Female Heparin Humans Male Mice Middle Aged Osteosarcoma Thrombin Venous Thrombosis Young Adult

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