ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.

Heuckmann JM, Hölzel M, Sos ML, Heynck S, Balke-Want H, Koker M, Peifer M, Weiss J, Lovly CM, Grütter C, Rauh D, Pao W, Thomas RK
Clin Cancer Res. 2011 17 (23): 7394-401

PMID: 21948233 · PMCID: PMC3382103 · DOI:10.1158/1078-0432.CCR-11-1648

MeSH Terms (18)

Anaplastic Lymphoma Kinase Antineoplastic Agents Cell Cycle Proteins Cell Line, Tumor Crizotinib Drug Resistance, Neoplasm Humans Lung Neoplasms Microtubule-Associated Proteins Mutation Neuroblastoma Oncogene Proteins, Fusion Polymorphism, Single Nucleotide Pyrazoles Pyridines Pyrimidines Receptor Protein-Tyrosine Kinases Serine Endopeptidases

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