Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.

Chmielecki J, Peifer M, Viale A, Hutchinson K, Giltnane J, Socci ND, Hollis CJ, Dean RS, Yenamandra A, Jagasia M, Kim AS, Davé UP, Thomas RK, Pao W
Genes Chromosomes Cancer. 2012 51 (1): 54-65

PMID: 21938754 · DOI:10.1002/gcc.20930

MeSH Terms (21)

Adult Algorithms Amino Acid Sequence Base Sequence Cell Line, Tumor Computational Biology Cytoskeletal Proteins Gene Order HEK293 Cells Humans K562 Cells Karyotyping Male Molecular Sequence Data Myeloproliferative Disorders Oncogene Proteins, Fusion Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Protein-Tyrosine Kinases Sequence Alignment Sequence Analysis, DNA Translocation, Genetic

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