Formation of a N2-dG:N2-dG carbinolamine DNA cross-link by the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N2-dG adduct.

Huang H, Wang H, Kozekova A, Rizzo CJ, Stone MP
J Am Chem Soc. 2011 133 (40): 16101-10

PMID: 21916419 · PMCID: PMC3187658 · DOI:10.1021/ja205145q

MeSH Terms (8)

Aldehydes Cross-Linking Reagents DNA Adducts Hydrogen Bonding Intercalating Agents Molecular Dynamics Simulation Nuclear Magnetic Resonance, Biomolecular Stereoisomerism

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