Characterization of a high-purity germanium detector for small-animal SPECT.

Johnson LC, Campbell DL, Hull EL, Peterson TE
Phys Med Biol. 2011 56 (18): 5877-88

PMID: 21852723 · PMCID: PMC3178965 · DOI:10.1088/0031-9155/56/18/007

We present an initial evaluation of a mechanically cooled, high-purity germanium double-sided strip detector as a potential gamma camera for small-animal SPECT. It is 90 mm in diameter and 10 mm thick with two sets of 16 orthogonal strips that have a 4.5 mm width with a 5 mm pitch. We found an energy resolution of 0.96% at 140 keV, an intrinsic efficiency of 43.3% at 122 keV and a FWHM spatial resolution of approximately 1.5 mm. We demonstrated depth-of-interaction estimation capability through comparison of pinhole acquisitions with a point source on and off axes. Finally, a flood-corrected flood image exhibited a strip-level uniformity of less than 1%. This high-purity germanium offers many desirable properties for small-animal SPECT.

MeSH Terms (12)

Animals Electromagnetic Fields Equipment Design Gamma Cameras Germanium Image Enhancement Models, Animal Particle Accelerators Phantoms, Imaging Reproducibility of Results Sensitivity and Specificity Tomography, Emission-Computed, Single-Photon

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