The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation.

Brooks JD, Musiek ES, Koestner TR, Stankowski JN, Howard JR, Brunoldi EM, Porta A, Zanoni G, Vidari G, Morrow JD, Milne GL, McLaughlin B
J Neurochem. 2011 119 (3): 604-16

PMID: 21838782 · PMCID: PMC3640263 · DOI:10.1111/j.1471-4159.2011.07422.x

MeSH Terms (11)

Animals Cell Line Fatty Acids Isoprostanes Macrophage Activation Macrophages Mice NF-kappa B Oxidation-Reduction Oxidative Stress Transcription, Genetic

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