PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression.

Zhou W, Dowell DR, Geraci MW, Blackwell TS, Collins RD, Polosukhin VV, Lawson WE, Wu P, Sussan T, Biswal S, Goleniewska K, O'Neal J, Newcomb DC, Toki S, Morrow JD, Peebles RS
Am J Physiol Lung Cell Mol Physiol. 2011 301 (4): L615-22

PMID: 21764988 · PMCID: PMC3774255 · DOI:10.1152/ajplung.00224.2010

MeSH Terms (24)

Acute Lung Injury Animals Apoptosis Bleomycin Bronchoalveolar Lavage Fluid Epoprostenol F2-Isoprostanes Female Gas Chromatography-Mass Spectrometry Gene Expression Humans Immunohistochemistry Lung Mice Mice, Transgenic NAD(P)H Dehydrogenase (Quinone) Polymerase Chain Reaction Prostaglandin-Endoperoxide Synthases Reactive Oxygen Species Receptors, Epoprostenol Respiratory Function Tests Respiratory Mucosa Signal Transduction Survival Rate

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