A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport.

Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E, Rudnick G, Noskov SY, DeFelice LJ, Meiler J, Blakely RD
J Biol Chem. 2011 286 (35): 30823-30836

PMID: 21730057 · PMCID: PMC3162443 · DOI:10.1074/jbc.M111.250308

MeSH Terms (18)

Animals Asparagine Chlorides Cysteine Electrophysiology HeLa Cells Humans Ions Mutagenesis, Site-Directed Neurotransmitter Agents Norepinephrine Oocytes Patch-Clamp Techniques Plasmids Rats Serotonin Serotonin Plasma Membrane Transport Proteins Xenopus laevis

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