Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy.

Gong IY, Tirona RG, Schwarz UI, Crown N, Dresser GK, Larue S, Langlois N, Lazo-Langner A, Zou G, Roden DM, Stein CM, Rodger M, Carrier M, Forgie M, Wells PS, Kim RB
Blood. 2011 118 (11): 3163-71

PMID: 21725053 · DOI:10.1182/blood-2011-03-345173

MeSH Terms (18)

Adult Aged Anticoagulants Aryl Hydrocarbon Hydroxylases Cohort Studies Cytochrome P-450 CYP2C9 Dose-Response Relationship, Drug Drug Resistance Female Humans Male Middle Aged Mixed Function Oxygenases Pharmacogenetics Polymorphism, Single Nucleotide Vitamin K Epoxide Reductases Warfarin Whole Blood Coagulation Time

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