The norepinephrine transporter inhibitor reboxetine reduces stimulant effects of MDMA ("ecstasy") in humans.

Hysek CM, Simmler LD, Ineichen M, Grouzmann E, Hoener MC, Brenneisen R, Huwyler J, Liechti ME
Clin Pharmacol Ther. 2011 90 (2): 246-55

PMID: 21677639 · DOI:10.1038/clpt.2011.78

MeSH Terms (18)

3,4-Methylenedioxyamphetamine Adrenergic Uptake Inhibitors Adult Blood Pressure Cross-Over Studies Double-Blind Method Drug Interactions Female Hallucinogens Heart Rate Humans Male Morpholines N-Methyl-3,4-methylenedioxyamphetamine Norepinephrine Norepinephrine Plasma Membrane Transport Proteins Reboxetine Young Adult

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