Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.

Yan F, Cao H, Cover TL, Washington MK, Shi Y, Liu L, Chaturvedi R, Peek RM, Wilson KT, Polk DB
J Clin Invest. 2011 121 (6): 2242-53

PMID: 21606592 · PMCID: PMC3104743 · DOI:10.1172/JCI44031

MeSH Terms (24)

Administration, Rectal Animals Apoptosis Bacterial Proteins Colitis Dextran Sulfate Drug Evaluation, Preclinical Enzyme Activation Epithelial Cells ErbB Receptors Hydrogels Intestinal Mucosa Lactobacillus rhamnosus Mice Mice, Inbred C57BL Microspheres Oxazolone Permeability Probiotics Proto-Oncogene Proteins c-akt Quinazolines Recombinant Proteins Signal Transduction Tyrphostins

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