Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit.

Van Eps N, Preininger AM, Alexander N, Kaya AI, Meier S, Meiler J, Hamm HE, Hubbell WL
Proc Natl Acad Sci U S A. 2011 108 (23): 9420-4

PMID: 21606326 · PMCID: PMC3111277 · DOI:10.1073/pnas.1105810108

MeSH Terms (19)

Amino Acid Sequence Animals Cell Membrane Cross-Linking Reagents Electron Spin Resonance Spectroscopy GTP-Binding Protein alpha Subunits GTP-Binding Proteins Guanosine Diphosphate Guanosine Triphosphate Models, Molecular Molecular Sequence Data Mutation Protein Binding Protein Structure, Secondary Protein Structure, Tertiary Rats Receptors, G-Protein-Coupled Rhodopsin Spin Labels

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