Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.

Lewis AS, Vaidya SP, Blaiss CA, Liu Z, Stoub TR, Brager DH, Chen X, Bender RA, Estep CM, Popov AB, Kang CE, Van Veldhoven PP, Bayliss DA, Nicholson DA, Powell CM, Johnston D, Chetkovich DM
J Neurosci. 2011 31 (20): 7424-40

PMID: 21593326 · PMCID: PMC3169171 · DOI:10.1523/JNEUROSCI.0936-11.2011

MeSH Terms (15)

Animals Cyclic Nucleotide-Gated Cation Channels Depression Gene Deletion Genetic Therapy Hippocampus Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Membrane Proteins Mice Mice, Inbred C57BL Mice, Knockout Peroxins Potassium Channels Protein Subunits Protein Transport

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