Multi-institutional phase II study of selumetinib in patients with metastatic biliary cancers.

Bekaii-Saab T, Phelps MA, Li X, Saji M, Goff L, Kauh JS, O'Neil BH, Balsom S, Balint C, Liersemann R, Vasko VV, Bloomston M, Marsh W, Doyle LA, Ellison G, Grever M, Ringel MD, Villalona-Calero MA
J Clin Oncol. 2011 29 (17): 2357-63

PMID: 21519026 · PMCID: PMC3107751 · DOI:10.1200/JCO.2010.33.9473

MeSH Terms (19)

Adult Aged Benzimidazoles Biliary Tract Neoplasms Extracellular Signal-Regulated MAP Kinases Female Humans Male MAP Kinase Kinase 1 MAP Kinase Kinase 2 Middle Aged Mutation Neoplasm Metastasis Phosphorylation Proto-Oncogene Proteins Proto-Oncogene Proteins B-raf Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins p21(ras) ras Proteins

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