Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humans.

Soutto M, Belkhiri A, Piazuelo MB, Schneider BG, Peng D, Jiang A, Washington MK, Kokoye Y, Crowe SE, Zaika A, Correa P, Peek RM, El-Rifai W
J Clin Invest. 2011 121 (5): 1753-67

PMID: 21490402 · PMCID: PMC3083788 · DOI:10.1172/JCI43922

MeSH Terms (19)

Animals Disease Progression Gastric Mucosa Gene Expression Profiling Humans I-kappa B Proteins Inflammation Mice Mice, Inbred C57BL Mice, Knockout NF-kappa B NF-KappaB Inhibitor alpha Oligonucleotide Array Sequence Analysis Peptides Phosphorylation Stomach Neoplasms Trefoil Factor-1 Tumor Necrosis Factor-alpha Tumor Suppressor Proteins

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