Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene.

Stairs DB, Bayne LJ, Rhoades B, Vega ME, Waldron TJ, Kalabis J, Klein-Szanto A, Lee JS, Katz JP, Diehl JA, Reynolds AB, Vonderheide RH, Rustgi AK
Cancer Cell. 2011 19 (4): 470-83

PMID: 21481789 · PMCID: PMC3077713 · DOI:10.1016/j.ccr.2011.02.007

MeSH Terms (16)

Animals Cadherins Carcinoma, Squamous Cell Catenins Cell Differentiation Cell Line, Tumor Cell Proliferation Esophageal Neoplasms Fibroblasts Genes, Tumor Suppressor Humans Inflammation Mice Mouth Neoplasms Myeloid Cells NF-kappa B

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