The E3 ubiquitin ligase- and protein phosphatase 2A (PP2A)-binding domains of the Alpha4 protein are both required for Alpha4 to inhibit PP2A degradation.

LeNoue-Newton M, Watkins GR, Zou P, Germane KL, McCorvey LR, Wadzinski BE, Spiller BW
J Biol Chem. 2011 286 (20): 17665-71

PMID: 21454489 · PMCID: PMC3093842 · DOI:10.1074/jbc.M111.222414

MeSH Terms (17)

Adaptor Proteins, Signal Transducing Amino Acid Motifs Animals Binding Sites Crystallography, X-Ray HEK293 Cells Humans Intercellular Signaling Peptides and Proteins Intracellular Signaling Peptides and Proteins Mice Molecular Chaperones Phosphoproteins Protein Phosphatase 2 Protein Structure, Tertiary Ubiquitin Ubiquitin-Protein Ligases Ubiquitination

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