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A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance.

Miller TW, Balko JM, Ghazoui Z, Dunbier A, Anderson H, Dowsett M, González-Angulo AM, Mills GB, Miller WR, Wu H, Shyr Y, Arteaga CL
Clin Cancer Res. 2011 17 (7): 2024-34

PMID: 21346144 · PMCID: PMC3221728 · DOI:10.1158/1078-0432.CCR-10-2567

MeSH Terms (28)

Anastrozole Antineoplastic Agents, Hormonal Biomarkers, Tumor Breast Neoplasms Cell Line, Tumor Cell Proliferation Chemotherapy, Adjuvant Disease-Free Survival Drug Resistance, Neoplasm Estrogen Receptor Modulators Female Gene Expression Profiling Genetic Association Studies Humans Kaplan-Meier Estimate Ki-67 Antigen Letrozole Neoadjuvant Therapy Neoplasm Recurrence, Local Neoplasms, Hormone-Dependent Nitriles Oligonucleotide Array Sequence Analysis Proportional Hazards Models Proto-Oncogene Proteins c-myc RNA Interference Tamoxifen Treatment Outcome Triazoles

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