The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation.

Jun D, Garat C, West J, Thorn N, Chow K, Cleaver T, Sullivan T, Torchia EC, Childs C, Shade T, Tadjali M, Lara A, Nozik-Grayck E, Malkoski S, Sorrentino B, Meyrick B, Klemm D, Rojas M, Wagner DH, Majka SM
Stem Cells. 2011 29 (4): 725-35

PMID: 21312316 · PMCID: PMC3322548 · DOI:10.1002/stem.604

MeSH Terms (12)

Animals Bleomycin Cell Proliferation Familial Primary Pulmonary Hypertension Hypertension, Pulmonary Lung Injury Mesenchymal Stem Cells Mice Mice, Inbred C57BL Polymerase Chain Reaction Pulmonary Fibrosis T-Lymphocytes

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