Hepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver.

Winnick JJ, An Z, Ramnanan CJ, Smith M, Irimia JM, Neal DW, Moore MC, Roach PJ, Cherrington AD
Diabetes. 2011 60 (2): 398-407

PMID: 21270252 · PMCID: PMC3028338 · DOI:10.2337/db10-0592

MeSH Terms (17)

AMP-Activated Protein Kinases Analysis of Variance Animals Blood Glucose Blotting, Western Dogs Fatty Acids, Nonesterified Female Fructose Glucagon Insulin Liver Liver Glycogen Male Portal Vein Reverse Transcriptase Polymerase Chain Reaction Signal Transduction

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