18FDG-PET predicts pharmacodynamic response to OSI-906, a dual IGF-1R/IR inhibitor, in preclinical mouse models of lung cancer.

McKinley ET, Bugaj JE, Zhao P, Guleryuz S, Mantis C, Gokhale PC, Wild R, Manning HC
Clin Cancer Res. 2011 17 (10): 3332-40

PMID: 21257723 · PMCID: PMC3122480 · DOI:10.1158/1078-0432.CCR-10-2274

MeSH Terms (19)

Adenocarcinoma Adenocarcinoma of Lung Animals Cell Line, Tumor Drug Evaluation, Preclinical Female Fluorodeoxyglucose F18 Humans Imidazoles Lung Neoplasms Mice Mice, Nude Positron-Emission Tomography Prognosis Protein Kinase Inhibitors Pyrazines Receptor, IGF Type 1 Receptor, Insulin Xenograft Model Antitumor Assays

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