The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure.

da-Silva WS, Ribich S, Arrojo e Drigo R, Castillo M, Patti ME, Bianco AC
FEBS Lett. 2011 585 (3): 539-44

PMID: 21237159 · PMCID: PMC3133948 · DOI:10.1016/j.febslet.2010.12.044

MeSH Terms (21)

Adipocytes, Brown Animals Cell Line Cells, Cultured Dietary Fats Energy Metabolism Gene Expression Regulation Gene Knockout Techniques Glucose Intolerance Humans Iodide Peroxidase Lipid Metabolism Male Mice Mice, Inbred C57BL Mice, Knockout Oxygen Consumption Phenylbutyrates RNA, Messenger Taurochenodeoxycholic Acid Triiodothyronine

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