Comparison of the inhibitory profiles of itraconazole and cimetidine in cytochrome P450 3A4 genetic variants.

Akiyoshi T, Saito T, Murase S, Miyazaki M, Murayama N, Yamazaki H, Guengerich FP, Nakamura K, Yamamoto K, Ohtani H
Drug Metab Dispos. 2011 39 (4): 724-8

PMID: 21212239 · PMCID: PMC3063718 · DOI:10.1124/dmd.110.036780

MeSH Terms (14)

14-alpha Demethylase Inhibitors Androgens Cimetidine Cytochrome P-450 CYP3A Cytochrome P-450 CYP3A Inhibitors Drug Interactions Enzyme Inhibitors Genetic Variation Heme Humans Hydroxytestosterones Itraconazole Recombinant Proteins Testosterone

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