Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

Weiss J, Sos ML, Seidel D, Peifer M, Zander T, Heuckmann JM, Ullrich RT, Menon R, Maier S, Soltermann A, Moch H, Wagener P, Fischer F, Heynck S, Koker M, Schöttle J, Leenders F, Gabler F, Dabow I, Querings S, Heukamp LC, Balke-Want H, Ansén S, Rauh D, Baessmann I, Altmüller J, Wainer Z, Conron M, Wright G, Russell P, Solomon B, Brambilla E, Brambilla C, Lorimier P, Sollberg S, Brustugun OT, Engel-Riedel W, Ludwig C, Petersen I, Sänger J, Clement J, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman D, Cappuzzo F, Ligorio C, Damiani S, Hallek M, Beroukhim R, Pao W, Klebl B, Baumann M, Buettner R, Ernestus K, Stoelben E, Wolf J, Nürnberg P, Perner S, Thomas RK
Sci Transl Med. 2010 2 (62): 62ra93

PMID: 21160078 · PMCID: PMC3990281 · DOI:10.1126/scitranslmed.3001451

MeSH Terms (18)

Adenocarcinoma Adenocarcinoma of Lung Animals Apoptosis Blotting, Western Carcinoma, Non-Small-Cell Lung Cell Line Enzyme Inhibitors Gene Expression Regulation, Neoplastic Humans Lung Neoplasms Male Mice Mice, Nude Pyrimidines Receptor, Fibroblast Growth Factor, Type 1 RNA Interference Xenograft Model Antitumor Assays

Connections (1)

This publication is referenced by other Labnodes entities:

Links