The α₂β₁ integrin is a metastasis suppressor in mouse models and human cancer.

Ramirez NE, Zhang Z, Madamanchi A, Boyd KL, O'Rear LD, Nashabi A, Li Z, Dupont WD, Zijlstra A, Zutter MM
J Clin Invest. 2011 121 (1): 226-37

PMID: 21135504 · PMCID: PMC3007139 · DOI:10.1172/JCI42328

MeSH Terms (22)

Animals Base Sequence Biomarkers, Tumor Breast Neoplasms DNA Primers Female Genes, erbB-2 Humans Integrin alpha2beta1 In Vitro Techniques Kaplan-Meier Estimate Male Mammary Neoplasms, Experimental Mice Mice, Knockout Mice, Transgenic Neoplasm Invasiveness Neoplasm Metastasis Prognosis Prostatic Neoplasms Tumor Stem Cell Assay Tumor Suppressor Proteins

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