Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension.

Vinh A, Chen W, Blinder Y, Weiss D, Taylor WR, Goronzy JJ, Weyand CM, Harrison DG, Guzik TJ
Circulation. 2010 122 (24): 2529-37

PMID: 21126972 · PMCID: PMC3064430 · DOI:10.1161/CIRCULATIONAHA.109.930446

MeSH Terms (19)

Abatacept Angiotensin II Animals Antihypertensive Agents B7-1 Antigen B7-2 Antigen CD28 Antigens Cells, Cultured Gene Deletion Hypertension Immunoconjugates Immunosuppressive Agents Ligands Lymphocyte Activation Mice Mice, Inbred C57BL Mice, Knockout Random Allocation T-Lymphocytes

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