The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis.

Singh K, Chaturvedi R, Barry DP, Coburn LA, Asim M, Lewis ND, Piazuelo MB, Washington MK, Vitek MP, Wilson KT
J Biol Chem. 2011 286 (5): 3839-50

PMID: 21115487 · PMCID: PMC3030385 · DOI:10.1074/jbc.M110.176719

MeSH Terms (13)

Animals Cells, Cultured Citrobacter rodentium Colon Cytokines Dextran Sulfate Disease Models, Animal Inflammatory Bowel Diseases Male Mice Mice, Inbred C57BL NF-kappa B Peptides

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