Hdac3 is essential for the maintenance of chromatin structure and genome stability.

Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan JL, Bonine-Summers AR, Wells CE, Kaiser JF, Washington MK, Zhao Z, Wagner FF, Sun ZW, Xia F, Holson EB, Khabele D, Hiebert SW
Cancer Cell. 2010 18 (5): 436-47

PMID: 21075309 · PMCID: PMC3004468 · DOI:10.1016/j.ccr.2010.10.022

MeSH Terms (22)

Acetylation Animals Carcinoma, Hepatocellular Cell Line, Tumor Chromatin Chromatin Assembly and Disassembly DNA Damage DNA Repair DNA Replication Down-Regulation Gene Expression Regulation, Neoplastic Genomic Instability Histone Deacetylases Histones Humans Liver Neoplasms, Experimental Mice Nuclear Receptor Co-Repressor 1 Nuclear Receptor Co-Repressor 2 RNA, Messenger RNA Interference S Phase

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